Add wos sample results library
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abstract: 'Background: Due to underrepresentation of racial/ethnic minority and
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low-income groups in clinical studies, there is a call to improve the
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recruitment and retention of these populations in research. Pilot
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studies can test recruitment and retention practices for better
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inclusion of medically underserved children and families in sub-sequent
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clinical trials. We examined this using a school-based asthma
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intervention, in preparation for a larger clinical trial in which our
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goal is to include an underserved study population.Methods: We recruited
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children with poorly controlled asthma in a two-site pilot cluster
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randomized controlled trial of school-supervised asthma therapy versus
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enhanced usual care (receipt of an educational asthma work-book). We
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sought a study population with a high percentage of children and
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families from racial/ethnic minority and low-income groups. The primary
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outcome of the pilot trial was recruitment/retention over 12 months.
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Strategies used to facilitate recruitment/retention of this study
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population included engaging pre-trial multi-level stakeholders,
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selecting trial sites with high percentages of underserved children and
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families, training diverse medical providers to recruit participants,
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conducting remote trial assessments, and providing multi-lingual study
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materials.Results: Twenty-six children {[}42.3\% female, 11.5\% Black,
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30.8\% Multiracial (Black \& other), 76.9\% Hispanic, and 92.3\% with
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family income below \$40,000] and their caregivers were enrolled in the
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study, which represents 55.3\% of those initially referred by their
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provider, with 96.2\%, 92.3\%, and 96.2\% retention at 3-, 6-, and 12
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-month follow-up, respectively.Conclusion: Targeted strategies
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facilitated the inclusion of a medically underserved population of
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children and families in our pilot study, prior to expanding to a larger
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trial.'
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affiliation: 'O''Donoghue, J (Corresponding Author), S5-828,55 Lake Ave N, Worcester,
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MA 01655 USA.
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O''Donoghue, Julia; Hoque, Shushmita; Mizrahi, Raphael; Spano, Michelle; Trivedi,
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Michelle, Univ Massachusetts, Dept Pediat, Div Pulmonol, Chan Med Sch, Worcester,
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MA USA.
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Luther, Janki, Washington Univ, Dept Med, Sch Med, St Louis, MO USA.
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Crawford, Sybil, Univ Massachusetts, Dept Med, Chan Med Sch, Worcester, MA USA.
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Frisard, Christine; Lemon, Stephenie C.; Rosal, Milagros; Pbert, Lori; Trivedi,
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Michelle, Univ Massachusetts, Dept Populat \& Quantitat Hlth Sci, Chan Med Sch,
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Worcester, MA USA.
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Garg, Arvin, Univ Massachusetts, Dept Pediat, Chan Med Sch, Worcester, MA USA.
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Byatt, Nancy, Univ Massachusetts, Dept Psychiat, Chan Med Sch, Worcester, MA USA.
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O''Donoghue, Julia, S5-828,55 Lake Ave N, Worcester, MA 01655 USA.'
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article-number: '106884'
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author: O'Donoghue, Julia and Luther, Janki and Hoque, Shushmita and Mizrahi, Raphael
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and Spano, Michelle and Frisard, Christine and Garg, Arvin and Crawford, Sybil and
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Byatt, Nancy and Lemon, Stephenie C. and Rosal, Milagros and Pbert, Lori and Trivedi,
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Michelle
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author-email: julia.odonoghue@spectrumhealth.org
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author_list:
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- family: O'Donoghue
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given: Julia
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- family: Luther
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given: Janki
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- family: Hoque
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given: Shushmita
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- family: Mizrahi
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given: Raphael
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- family: Spano
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given: Michelle
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- family: Frisard
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given: Christine
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- family: Garg
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given: Arvin
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- family: Crawford
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given: Sybil
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- family: Byatt
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given: Nancy
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- family: Lemon
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given: Stephenie C.
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- family: Rosal
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given: Milagros
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- family: Pbert
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given: Lori
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- family: Trivedi
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given: Michelle
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da: '2023-09-28'
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doi: 10.1016/j.cct.2022.106884
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earlyaccessdate: AUG 2022
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eissn: 1559-2030
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files: []
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issn: 1551-7144
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journal: CONTEMPORARY CLINICAL TRIALS
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keywords: Pilot test; Recruitment; Retention; Asthma; Clinical trials; Underserved
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keywords-plus: POPULATIONS; OPPORTUNITIES; DISPARITIES; MINORITY; WOMEN; CARE
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language: English
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month: SEP
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number-of-cited-references: '35'
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papis_id: fe2358664d322863fdb5d8ca50764ddd
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ref: Odonoghue2022strategiesimprove
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times-cited: '1'
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title: 'Strategies to improve the recruitment and retention of underserved children
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and families in clinical trials: A case example of a school-supervised asthma therapy
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pilot'
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type: Article
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unique-id: WOS:000863129900001
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usage-count-last-180-days: '1'
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usage-count-since-2013: '1'
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volume: '120'
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web-of-science-categories: Medicine, Research \& Experimental; Pharmacology \& Pharmacy
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year: '2022'
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