Add wos sample results library
This commit is contained in:
parent
6305e61d1f
commit
19e409ad85
2173 changed files with 235628 additions and 20 deletions
|
|
@ -0,0 +1,132 @@
|
|||
abstract: 'Despite of the rapid development of the vaccines against the severe
|
||||
|
||||
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it will take
|
||||
|
||||
several months to have enough doses and the proper infrastructure to
|
||||
|
||||
vaccinate a good proportion of the world population. In this interim,
|
||||
|
||||
the accessibility to the Bacille Calmette-Guerin (BCG) may mitigate the
|
||||
|
||||
pandemic impact in some countries and the BCG vaccine offers significant
|
||||
|
||||
advantages and flexibility in the way clinical vaccines are
|
||||
|
||||
administered. BCG vaccination is a highly cost-effective intervention
|
||||
|
||||
against tuberculosis (TB) and many low-and lower-middle-income countries
|
||||
|
||||
would likely have the infrastructure, and health care personnel
|
||||
|
||||
sufficiently familiar with the conventional TB vaccine to mount
|
||||
|
||||
full-scale efforts to administer novel BCG-based vaccine for COVID-19.
|
||||
|
||||
This suggests the potential for BCG to overcome future barriers to
|
||||
|
||||
vaccine roll-out in the countries where health systems are fragile and
|
||||
|
||||
where the effects of this new coronavirus could be catastrophic. Many
|
||||
|
||||
studies have reported cross-protective effects of the BCG vaccine toward
|
||||
|
||||
non-tuberculosis related diseases. Mechanistically, this
|
||||
|
||||
cross-protective effect of the BCG vaccine can be explained, in part, by
|
||||
|
||||
trained immunity, a recently discovered program of innate immune memory,
|
||||
|
||||
which is characterized by non-permanent epigenetic reprogramming of
|
||||
|
||||
macrophages that leads to increased inflammatory cytokine production and
|
||||
|
||||
consequently potent immune responses. In this review, we summarize
|
||||
|
||||
recent work highlighting the potential use of BCG for the treatment
|
||||
|
||||
respiratory infectious diseases and ongoing SARS-CoV-2 clinical trials.
|
||||
|
||||
In situations where no other specific prophylactic tools are available,
|
||||
|
||||
the BCG vaccine could be used as a potential adjuvant, to decrease
|
||||
|
||||
sickness of SARS-CoV-2 infection and/or to mitigate the effects of
|
||||
|
||||
concurrent respiratory infections.'
|
||||
affiliation: 'Ochando, J (Corresponding Author), Inst Salud Carlos III, Dept Immunol,
|
||||
Transplant Immunol Unit, Natl Ctr Microbiol, Madrid, Spain.
|
||||
|
||||
Ochando, J (Corresponding Author), Icahn Sch Med Mt Sinai, Dept Oncol Sci, New York,
|
||||
NY 10029 USA.
|
||||
|
||||
Gonzalez-Perez, Maria; Ochando, Jordi, Inst Salud Carlos III, Dept Immunol, Transplant
|
||||
Immunol Unit, Natl Ctr Microbiol, Madrid, Spain.
|
||||
|
||||
Sanchez-Tarjuelo, Rodrigo; Ochando, Jordi, Icahn Sch Med Mt Sinai, Dept Oncol Sci,
|
||||
New York, NY 10029 USA.
|
||||
|
||||
Shor, Boris, Manhattan BioSolut, New York, NY USA.
|
||||
|
||||
Nistal-Villan, Estanislao, Univ San Pablo Ctr Estudios Univ CEU, Fac Farm, Microbiol
|
||||
Sect, Dept Ciencias Farmaceut \& Salud, Madrid, Spain.
|
||||
|
||||
Nistal-Villan, Estanislao, Univ San Pablo CEU, Inst Med Mol Aplicada IMMA, Fac Med,
|
||||
Madrid, Spain.'
|
||||
article-number: '632478'
|
||||
author: Gonzalez-Perez, Maria and Sanchez-Tarjuelo, Rodrigo and Shor, Boris and Nistal-Villan,
|
||||
Estanislao and Ochando, Jordi
|
||||
author-email: Jordi.ochando@mssm.edu.edu
|
||||
author_list:
|
||||
- family: Gonzalez-Perez
|
||||
given: Maria
|
||||
- family: Sanchez-Tarjuelo
|
||||
given: Rodrigo
|
||||
- family: Shor
|
||||
given: Boris
|
||||
- family: Nistal-Villan
|
||||
given: Estanislao
|
||||
- family: Ochando
|
||||
given: Jordi
|
||||
da: '2023-09-28'
|
||||
doi: 10.3389/fimmu.2021.632478
|
||||
files: []
|
||||
issn: 1664-3224
|
||||
journal: FRONTIERS IN IMMUNOLOGY
|
||||
keywords: 'Bacille Calmette-Guerin; SARS-CoV-2; vaccination; trained immunity;
|
||||
|
||||
cross-protection'
|
||||
keywords-plus: 'BACILLUS-CALMETTE-GUERIN; RESPIRATORY SYNCYTIAL VIRUS; TRAINED IMMUNITY;
|
||||
|
||||
NONSPECIFIC PROTECTION; GUINEA-BISSAU; RECOMBINANT; INFECTION;
|
||||
|
||||
RESPONSES; EFFICACY; MEMORY'
|
||||
language: English
|
||||
month: MAR 8
|
||||
number-of-cited-references: '68'
|
||||
orcid-numbers: 'Ochando, jordi/0000-0001-7037-1681
|
||||
|
||||
Nistal-Villan, Estanislao/0000-0003-2458-8833
|
||||
|
||||
Gonzalez Perez, Maria/0000-0003-0838-4734
|
||||
|
||||
Sanchez Tarjuelo, Rodrigo/0000-0002-3252-2722'
|
||||
papis_id: 409cc5f0651b9c4f28972a54ac5577cc
|
||||
ref: Gonzalezperez2021bcgvaccine
|
||||
researcherid-numbers: 'Ochando, jordi/ABE-2358-2020
|
||||
|
||||
Nistal-Villan, Estanislao/GWM-7994-2022
|
||||
|
||||
Nistal-Villan, Estanislao/C-6122-2015
|
||||
|
||||
'
|
||||
tags:
|
||||
- review
|
||||
times-cited: '43'
|
||||
title: 'The BCG Vaccine for COVID-19: First Verdict and Future Directions'
|
||||
type: Review
|
||||
unique-id: WOS:000630922700001
|
||||
usage-count-last-180-days: '0'
|
||||
usage-count-since-2013: '4'
|
||||
volume: '12'
|
||||
web-of-science-categories: Immunology
|
||||
year: '2021'
|
||||
Loading…
Add table
Add a link
Reference in a new issue