114 lines
3.6 KiB
YAML
114 lines
3.6 KiB
YAML
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abstract: 'The present study was undertaken to assess the health-related quality of
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life (HRQoL) and burden of illness due to pain and its treatment for
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patients with peripheral neuropathic pain (PNP). It is the first step in
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finding reliable instruments/targets to evaluate treatment outcome in
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this patient population. Study population consisted of 126 patients
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suffering from neuropathic, pain due to a peripheral nerve or root
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lesion, recruited from two multidisciplinary pain clinics. HRQoL was
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examined using Short Form 36 (SF-36) Health Survey and Nottingham Health
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Profile (NHP). Pain intensity in four categories (at rest and evoked by
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movement, touch and cold) was rated on a visual analogue scale (VAS).
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Degree of discomfort from pain and 25 symptoms related to pain and
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side-effects was also assessed. Reduction in workload due to pain was
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recorded, as was the pain relief from previous and current treatments
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and the reasons for discontinuing previous treatments.
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All dimensions in SF-36 and NHP were significantly impaired. SF-36 was a
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valid instrument for describing the impact of pain on the HRQoL of
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patients with PNP. NHP had a lower reliability but has other advantages
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that might be of importance. Many patients experienced poor pain relief
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from ongoing pain treatments. Most previous treatments were discontinued
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owing to lack of efficacy and/or severe side-effects. Many patients
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experienced a high intensity of at least one type of pain; median VAS
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for the highest pain intensity score of each patient (any type of pain)
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was 74/100. Besides pain, patients were most bothered by difficulty in
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sleeping, lack of energy, drowsiness, difficulty in concentrating and
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dry mouth. Employment status was reduced owing to pain in 52\% of the
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patients.
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The intense pain, other troublesome symptoms, limited efficacy and
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tolerability of available treatments, together with the impaired health
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and reduced work status, amount to a substantial burden for patients
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with PNP. (C) 2001 European Federation of Chapters of the International
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Association for the Study of Pain.'
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affiliation: 'Astra Pain Control AB, SE-15185 Sodertalje, Sweden.
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Univ Uppsala Hosp, Dept Anesthesiol \& Intens Care, Acad Hosp, SE-75105 Uppsala,
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Sweden.
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Danderyd Hosp, Dept Anesthesiol \& Intens Care, SE-18288 Stockholm, Sweden.'
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author: Meyer-Rosberg, K and Kvarnstrom, A and Kinnman, E and Gordh, T and Nordfors,
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LO and Kristofferson, A
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author-email: karin.meyer-rosberg@quintiles.com
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author_list:
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- family: Meyer-Rosberg
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given: K
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- family: Kvarnstrom
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given: A
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- family: Kinnman
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given: E
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- family: Gordh
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given: T
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- family: Nordfors
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given: LO
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- family: Kristofferson
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given: A
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da: '2023-09-28'
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doi: 10.1053/eujp.2001.0259
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eissn: 1532-2149
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files: []
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issn: 1090-3801
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journal: EUROPEAN JOURNAL OF PAIN
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keywords: 'peripheral neuropathic pain; peripheral nerve injury; nerve root lesion;
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SF-36; Nottingham Health Profile; health related quality of life; rating
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scale'
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keywords-plus: 'QUALITY-OF-LIFE; RANDOMIZED CONTROLLED TRIAL; HEALTH SURVEY SF-36;
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GABAPENTIN; VALIDITY; DISEASE'
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language: English
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number: '4'
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number-of-cited-references: '25'
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orcid-numbers: Gordh, Torsten/0000-0003-1454-3148
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pages: 379-389
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papis_id: 5a20a2b52ded89796b26acf6eb1de806
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ref: Meyerrosberg2001peripheralneuropathi
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times-cited: '173'
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title: Peripheral neuropathic pain - a multidimensional burden for patients
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type: Article
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unique-id: WOS:000173508300006
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usage-count-last-180-days: '1'
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usage-count-since-2013: '17'
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volume: '5'
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web-of-science-categories: Anesthesiology; Clinical Neurology; Neurosciences
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year: '2001'
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