wow-inequalities/02-data/intermediate/wos_sample/348fe0f3957f236e42d4479287d5334b-mcmahon-james-h.-an/info.yaml

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2023-09-28 14:46:10 +00:00
abstract: 'Operational research to identify factors predicting poor clinical
outcomes is critical to maximize patient care and prolong first-line
regimens for those receiving free antiretroviral therapy (ART) in India.
We sought to identify social or clinical factors amenable to
intervention that predict virological outcomes after 12 months of ART.
We examined a retrospective cohort of consecutive adults initiating free
nonnucleoside reverse transcriptase inhibitor-based regimens.
Individuals remaining in care 12 months post-ART initiation were tested
for HIV viral load and surveyed to identify barriers and facilitators to
adherence, and to determine clinic travel times and associated costs.
Uni- and multivariate logistic regression identified factors predicting
HIV viral load >200 copies/mL after 12 months of ART. Of 230 adults
initiating ART, 10\% of patients died, 8\% transferred out, 5\% were
lost to follow-up, and 174/230 (76\%) completed 12 months of ART, the
questionnaire, and viral load testing. HIV viral load was <200 copies/mL
in 140/174 (80\%) patients. In multivariate models, being busy with work
or caring for others (OR 2.9, p < 0.01), having clinic transport times 3
hours (OR 3.0, p = 0.02), and alcohol use (OR 4.8, p = 0.03) predicted
viral load >200 copies/mL after 12 months of ART. Clinical outcomes
following ART are related to programmatic factors such as prolonged
travel time and individual factors such as being busy with family or
using alcohol. Simple interventions that alter these factors should be
evaluated to improve clinical outcomes for populations receiving free
ART in similar settings.'
affiliation: 'McMahon, JH (Corresponding Author), Alfred Hosp, Infect Dis Unit, Melbourne,
Vic, Australia.
McMahon, James H.; Elliott, Julian H.; Lewin, Sharon R., Alfred Hosp, Infect Dis
Unit, Melbourne, Vic, Australia.
McMahon, James H.; Wanke, Christine; Jordan, Michael R., Tufts Univ, Sch Med, Dept
Publ Hlth \& Community Med, Boston, MA 02111 USA.
Manoharan, Anand; Jose, Hepsibah; Malini, Thabeetha; Kadavanu, Tony; Mathai, Dilip,
Christian Med Coll \& Hosp, Dept Med, Vellore, Tamil Nadu, India.
Mammen, Shoba, Christian Med Coll \& Hosp, Dept Clin Virol, Vellore, Tamil Nadu,
India.
Elliott, Julian H.; Lewin, Sharon R., Monash Univ, Dept Infect Dis, Melbourne, Vic
3004, Australia.
Elliott, Julian H.; Lewin, Sharon R., Burnet Inst, Melbourne, Vic, Australia.'
author: McMahon, James H. and Manoharan, Anand and Wanke, Christine and Mammen, Shoba
and Jose, Hepsibah and Malini, Thabeetha and Kadavanu, Tony and Jordan, Michael
R. and Elliott, Julian H. and Lewin, Sharon R. and Mathai, Dilip
author-email: ja.mcmahon@alfred.org.au
author_list:
- family: McMahon
given: James H.
- family: Manoharan
given: Anand
- family: Wanke
given: Christine
- family: Mammen
given: Shoba
- family: Jose
given: Hepsibah
- family: Malini
given: Thabeetha
- family: Kadavanu
given: Tony
- family: Jordan
given: Michael R.
- family: Elliott
given: Julian H.
- family: Lewin
given: Sharon R.
- family: Mathai
given: Dilip
da: '2023-09-28'
doi: 10.1080/09540121.2013.845282
eissn: 1360-0451
files: []
issn: 0954-0121
journal: AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV
keywords: 'HIV; intervention targets; antiretroviral therapy; India; virological
outcomes; adherence'
keywords-plus: 'DRUG-RESISTANCE; MEDICATION ADHERENCE; INCOME COUNTRIES; HIV; CARE;
CHENNAI; SUPPRESSION; PREDICTORS; RETENTION; CLINICS'
language: English
month: MAY 4
number: '5'
number-of-cited-references: '37'
orcid-numbers: 'McMahon, James/0000-0003-1460-5572
Lewin, Sharon Ruth/0000-0002-0330-8241'
pages: 559-566
papis_id: 56ece1e0bcabaca29a4120ed101cd65c
ref: Mcmahon2014targetsintervention
researcherid-numbers: 'Lewin, Sharon/Z-3297-2019
'
times-cited: '2'
title: Targets for intervention to improve virological outcomes for patients receiving
free antiretroviral therapy in Tamil Nadu, India
2023-10-01 08:15:07 +00:00
type: article
2023-09-28 14:46:10 +00:00
unique-id: WOS:000331337200006
usage-count-last-180-days: '0'
usage-count-since-2013: '2'
volume: '26'
web-of-science-categories: 'Health Policy \& Services; Public, Environmental \& Occupational
Health;
Psychology, Multidisciplinary; Respiratory System; Social Sciences,
Biomedical'
year: '2014'