wow-inequalities/02-data/intermediate/wos_sample/4319a1d1e56874bd733cd56a6792bc43-hansen-bjarke-brand/info.yaml

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abstract: 'Background Occupational medicine seeks to reduce sick leave; however,
evidence for an add-on effect to usual care is sparse. The objective of
the GOBACK trial was to test whether people with low back pain (LBP) in
physically demanding jobs and at risk of sick leave gain additional
benefit from a 3-month complex intervention that involves occupational
medicine consultations, a work-related evaluation and workplace
intervention plan, an optional workplace visit, and a physical activity
program, over a single hospital consultation and an MRI. Methods and
findings We enrolled people from the capital region of Denmark to an
open-label, parallel-group randomized controlled trial with a
superiority design from March 2014 through December 2015. In a hospital
setting 305 participants (99 women) with LBP and in physically demanding
jobs were randomized to occupational intervention (n = 153) or no
additional intervention (control group; n = 152) added to a single
hospital consultation giving a thorough explanation of the pain (i.e.,
clinical examination and MRI) and instructions to stay active and
continue working. Primary outcome was accumulated sick leave days due to
LBP during 6 months. Secondary outcomes were changes in neuropathic pain
(painDETECT questionnaire {[}PDQ]), pain 0-10 numerical rating scale
(NRS), Fear-Avoidance Beliefs Questionnaire (FABQ), Roland-Morris
Disability Questionnaire (RMDQ), Short Form Health Survey (SF-36) for
physical and mental health-related quality of life (HRQoL), and
self-assessed ability to continue working (range 0-10). An
intention-to-treat analysis of sick leave at 6 months showed no
significant difference between groups (mean difference in days
suggestively in favor of no additional intervention: 3.50 {[}95\% CI
-5.08 to 12.07], P = 0.42). Both groups showed significant improvements
in average pain score (NRS), disability (RMDQ), fear-avoidance beliefs
about physical activities and work (FABQ), and physical HRQoL (SF-36
physical component summary); there were no significant differences
between the groups in any secondary outcome. There was no statistically
significant improvement in neuropathic pain (PDQ score), mental HRQoL
(SF-36 mental component summary), and self-assessed ability to stay in
job. Four participants could not complete the MRI or the intervention
due to a claustrophobic attack or accentuated back pain. Workplace
visits may be an important element in the occupational intervention,
although not always needed. A per-protocol analysis that included the 40
participants in the intervention arm who received a workplace visit as
part of the additional occupational intervention did not show an add-on
benefit in terms of sick leave (available cases after 6 months, mean
difference: -0.43 days {[}95\% CI -12.8 to 11.94], P = 0.945). The main
limitations were the small number of sick leave days taken and that the
comprehensive use of MRI may limit generalization of the findings to
other settings, for example, general practice. Conclusions When given a
single hospital consultation and MRI, people in physically demanding
jobs at risk of sick leave due to LBP did not benefit from a complex
additional occupational intervention. Occupational interventions aimed
at limiting biopsychological obstacles (e.g., fear-avoidance beliefs and
behaviors), barriers in the workplace, and system barriers seem
essential to reduce sick leave in patients with LBP. This study
indicates that these obstacles and barriers may be addressed by thorough
usual care.'
affiliation: 'Hansen, BB (Corresponding Author), Copenhagen Univ Hosp, Parker Inst,
Bispebjerg, Denmark.
Hansen, BB (Corresponding Author), Copenhagen Univ Hosp, Parker Inst, Frederiksberg,
Denmark.
Hansen, BB (Corresponding Author), Copenhagen Univ Hosp, Dept Occupat \& Environm
Med, Bispebjerg, Denmark.
Hansen, BB (Corresponding Author), Copenhagen Univ Hosp, Dept Occupat \& Environm
Med, Frederiksberg, Denmark.
Hansen, Bjarke Brandt; Bliddal, Henning; Christensen, Robin; Kristensen, Lars Erik,
Copenhagen Univ Hosp, Parker Inst, Bispebjerg, Denmark.
Hansen, Bjarke Brandt; Bliddal, Henning; Christensen, Robin; Kristensen, Lars Erik,
Copenhagen Univ Hosp, Parker Inst, Frederiksberg, Denmark.
Hansen, Bjarke Brandt; Begtrup, Luise Moelenberg; Andreasen, Ditte Lundsgaard; Flachs,
Esben Meulengracht; Kryger, Ann Isabel, Copenhagen Univ Hosp, Dept Occupat \& Environm
Med, Bispebjerg, Denmark.
Hansen, Bjarke Brandt; Begtrup, Luise Moelenberg; Andreasen, Ditte Lundsgaard; Flachs,
Esben Meulengracht; Kryger, Ann Isabel, Copenhagen Univ Hosp, Dept Occupat \& Environm
Med, Frederiksberg, Denmark.
Kirkeskov, Lilli, Copenhagen Univ Hosp, Ctr Social Med, Bispebjerg, Denmark.
Kirkeskov, Lilli, Copenhagen Univ Hosp, Ctr Social Med, Frederiksberg, Denmark.
Boesen, Mikael, Copenhagen Univ Hosp, Dept Radiol, Bispebjerg, Denmark.
Boesen, Mikael, Copenhagen Univ Hosp, Dept Radiol, Frederiksberg, Denmark.
Christensen, Robin, Univ Southern Denmark, Odense Univ Hosp, Dept Clin Res, Res
Unit Rheumatol, Odense, Denmark.'
article-number: e1002898
author: Hansen, Bjarke Brandt and Kirkeskov, Lilli and Begtrup, Luise Moelenberg and
Boesen, Mikael and Bliddal, Henning and Christensen, Robin and Andreasen, Ditte
Lundsgaard and Kristensen, Lars Erik and Flachs, Esben Meulengracht and Kryger,
Ann Isabel
author-email: dr.bjarke@gmail.com
author_list:
- family: Hansen
given: Bjarke Brandt
- family: Kirkeskov
given: Lilli
- family: Begtrup
given: Luise Moelenberg
- family: Boesen
given: Mikael
- family: Bliddal
given: Henning
- family: Christensen
given: Robin
- family: Andreasen
given: Ditte Lundsgaard
- family: Kristensen
given: Lars Erik
- family: Flachs
given: Esben Meulengracht
- family: Kryger
given: Ann Isabel
da: '2023-09-28'
doi: 10.1371/journal.pmed.1002898
eissn: 1549-1676
files: []
issn: 1549-1277
journal: PLOS MEDICINE
keywords-plus: 'HEALTH-CARE; SICK-LEAVE; QUESTIONNAIRE; WORKPLACE; MANAGEMENT; WORKERS;
RETURN; RATES'
language: English
month: AUG
number: '8'
number-of-cited-references: '33'
orcid-numbers: 'Bliddal, Henning/0000-0002-7951-1668
Boesen, Mikael/0000-0002-8774-6563
Christensen, Robin/0000-0002-6600-0631
Hansen, Bjarke Brandt/0000-0002-4440-1960
Flachs, Esben Meulengracht/0000-0002-2252-8426'
papis_id: 0c7b316434483e8885b6c193555a90e0
ref: Hansen2019earlyoccupational
researcherid-numbers: 'Kristensen, Lars Erik/AAZ-2615-2020
'
times-cited: '9'
title: 'Early occupational intervention for people with low back pain in physically
demanding jobs: A randomized clinical trial'
2023-10-01 08:15:07 +00:00
type: article
2023-09-28 14:46:10 +00:00
unique-id: WOS:000489050500023
usage-count-last-180-days: '1'
usage-count-since-2013: '4'
volume: '16'
web-of-science-categories: Medicine, General \& Internal
year: '2019'