wow-inequalities/02-data/intermediate/wos_sample/13a9d25d1ebe54c8b1a45e7293177952-edlin-brian-r.-and/info.yaml

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2023-09-28 14:46:10 +00:00
abstract: 'The advent of highly effective antiviral regimens will make the
eradication of hepatitis C in high-income countries such as the United
States technically feasible. But eradicating hepatitis C will require
escalating our response to the epidemic in key domains, including
surveillance and epidemiology, prevention, screening, care and
treatment, policy, research, and advocacy. Surveillance must be nimble
enough to quickly assess the magnitude of new transmission patterns as
they emerge. Basic prevention strategies - community-based outreach and
education, testing and counseling, and access to sterile injection
equipment and opioid substitution therapies - must be scaled up and
adapted to target groups in which new epidemics are emerging. All adults
should be screened for hepatitis C, but special efforts must focus on
groups with increased prevalence through community outreach and rapid
testing. Government, industry, and payers must work together to assure
full access to health services and antiviral drugs for everyone who is
infected. Access to the new regimens must not be compromised by
excessively high prices or arbitrary payer restrictions. Partnerships
must be forged between hepatitis providers and programs that serve
people who inject illicit drugs. Healthcare providers and systems,
especially primary care practitioners, need education and training in
treating hepatitis C and caring for substance-using populations.
Services must be provided to the disadvantaged and stigmatized members
of society who bear a disproportionate burden of the epidemic.
Environments must be created where people who use drugs can receive
prevention and treatment services without shame or stigma. Action is
needed to end the policy of mass incarceration of people who use drugs,
reduce the stigma associated with substance use, support the human
rights of people who use drugs, expand social safety net services for
the poor and the homeless, remove the legal barriers to hepatitis C
prevention, and build public health infrastructure to reach, engage, and
serve marginalized populations. Governments must take action to bring
about these changes. Public health agencies must work with penal
institutions to provide prevention and treatment services, including
antiviral therapy, to those in need in jails and prisons or on probation
or parole. Research is needed to guide efforts in each of these domains.
Strong and sustained political advocacy will be needed to build and
sustain support for these measures. Leadership must be provided by
physicians, scientists, and the public health community in partnership
with community advocates and people living with or at risk for hepatitis
C. Eliminating hepatitis C from the United States is possible, but will
require a sustained national commitment to reach, test, treat, cure, and
prevent every case. With strong political leadership, societal
commitment, and community support, hepatitis C can be eradicated in the
United States. If this is to happen in our lifetimes, the time for
action is now. This article forms part of a symposium in Antiviral
Research on ``Hepatitis C: next steps toward global eradication.{''''} (C)
2014 Elsevier B.V. All rights reserved.'
affiliation: 'Edlin, BR (Corresponding Author), Natl Dev \& Res Inst, 71 West 23rd
St,4th Floor, New York, NY 10010 USA.
Edlin, Brian R., Weill Cornell Med Coll, New York, NY 10065 USA.
Winkelstein, Emily R., Natl Dev \& Res Inst, New York, NY 10010 USA.'
author: Edlin, Brian R. and Winkelstein, Emily R.
author-email: 'bredlin.nyc@gmail.com
winkelstein@ndri.org'
author_list:
- family: Edlin
given: Brian R.
- family: Winkelstein
given: Emily R.
da: '2023-09-28'
doi: 10.1016/j.antiviral.2014.07.015
eissn: 1872-9096
files: []
issn: 0166-3542
journal: ANTIVIRAL RESEARCH
keywords: 'Hepatitis C; Disease eradication; Epidemiology; Prevention; Antiviral
therapy; Social determinants of health'
keywords-plus: 'INJECTION-DRUG USERS; NEW-YORK-CITY; HUMAN-IMMUNODEFICIENCY-VIRUS;
SYRINGE EXCHANGE PROGRAMS; HEALTH-CARE-DELIVERY; INFECTIOUS-DISEASE;
SAN-FRANCISCO; PUBLIC-HEALTH; HIV-INFECTION; CORRECTIONAL FACILITY'
language: English
month: OCT
number-of-cited-references: '186'
orcid-numbers: Edlin, Brian R/0000-0001-8172-8797
pages: 79-93
papis_id: 5ab2c1947d38f9ced15d5e8f99ba45ea
ref: Edlin2014canhepatitis
researcherid-numbers: Edlin, Brian R/F-2966-2018
times-cited: '35'
title: Can hepatitis C be eradicated in the United States?
2023-10-01 08:15:07 +00:00
type: article
2023-09-28 14:46:10 +00:00
unique-id: WOS:000343352600010
usage-count-last-180-days: '1'
usage-count-since-2013: '36'
volume: '110'
web-of-science-categories: Pharmacology \& Pharmacy; Virology
year: '2014'