163 lines
5 KiB
YAML
163 lines
5 KiB
YAML
abstract: 'Background: Researchers have frequently encountered difficulties in the
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recruitment and retention of minorities resulting in their
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under-representation in clinical trials. This report describes the
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successful strategies of recruitment and retention of African Americans
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and Latinos in a randomized clinical trial to reduce smoking, depression
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and intimate partner violence during pregnancy. Socio-demographic
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characteristics and risk profiles of retained vs. non-retained women and
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lost to follow-up vs. dropped-out women are presented. In addition,
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subgroups of pregnant women who are less ( more) likely to be retained
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are identified.
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Methods: Pregnant African American women and Latinas who were
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Washington, DC residents, aged 18 years or more, and of 28 weeks
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gestational age or less were recruited at six prenatal care clinics.
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Potentially eligible women were screened for socio-demographic
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eligibility and the presence of the selected behavioral and
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psychological risks using an Audio Computer-Assisted Self-Interview.
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Eligible women who consented to participate completed a baseline
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telephone evaluation after which they were enrolled in the study and
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randomly assigned to either the intervention or the usual care group.
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Results: Of the 1,398 eligible women, 1,191 (85\%) agreed to participate
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in the study. Of the 1,191 women agreeing to participate, 1,070
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completed the baseline evaluation and were enrolled in the study and
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randomized, for a recruitment rate of 90\%. Of those enrolled, 1,044
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were African American women. A total of 849 women completed the study,
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for a retention rate of 79\%. Five percent dropped out and 12\% were
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lost-to-follow up. Women retained in the study and those not retained
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were not statistically different with regard to socio-demographic
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characteristics and the targeted risks. Retention strategies included
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financial and other incentives, regular updates of contact information
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which was tracked and monitored by a computerized data management system
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available to all project staff, and attention to cultural competence
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with implementation of study procedures by appropriately selected,
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trained, and supervised staff. Single, less educated, alcohol and drug
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users, non-working, and non-WIC women represent minority women with
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expected low retention rates.
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Conclusion: We conclude that with targeted recruitment and retention
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strategies, minority women will participate at high rates in behavioral
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clinical trials. We also found that women who drop out are different
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from women who are lost to follow-up, and require different strategies
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to optimize their completion of the study.'
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affiliation: 'Kiely, M (Corresponding Author), NICHD, NIH, DESPR, Collaborat Studies
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Unit, 6100 Execut Blvd,Rm 7B05, Rockville, MD 20852 USA.
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NICHD, NIH, DESPR, Collaborat Studies Unit, Rockville, MD 20852 USA.
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RTI Int, Stat \& Epidemiol Unit, Rockville, MD 20852 USA.
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Howard Univ, Coll Pharm Nursing \& Allied Hlth Sci, Div Allied Hlth Sci, Washington,
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DC 20059 USA.
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George Washington Univ, Med Ctr, Sch Publ Hlth \& Hlth Serv, Dept Prevent \& Community
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Hlth, Washington, DC 20037 USA.
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Georgetown Univ Hosp, Div Neonatol, Washington, DC 20007 USA.
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Care Of Allan A Johnson, Howard Univ, Coll Pharm Nursing \& Allied Hlth Sci, Div
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Allied Hlth Sci, Washington, DC 20059 USA.
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Res Triangle Inst Int, Stat \& Epidemiol Unit, Rockville, MD 20852 USA.
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Childrens Natl Med Ctr, Ctr Hlth Serv \& Community Res, Washington, DC 20010 USA.'
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article-number: '233'
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author: El-Khorazaty, M. Nabil and Johnson, Allan A. and Kiely, Michele and El-Mohandes,
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Ayman Ae and Subramanian, Siva and Laryea, Haziel A. and Murray, Kennan B. and Thornberry,
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Jutta S. and Joseph, Jill G.
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author-email: 'nek@rti.org
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ajohnson@Howard.edu
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kielym@nih.gov
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sphaxe@gwumc.edu
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SUBRAMAS@gunet.georgetown.edu
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hlaryea@howard.edu
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kennan17@yahoo.com
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jps@rti.org
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JJoseph@cnmc.org'
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author_list:
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- family: El-Khorazaty
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given: M. Nabil
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- family: Johnson
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given: Allan A.
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- family: Kiely
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given: Michele
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- family: El-Mohandes
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given: Ayman Ae
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- family: Subramanian
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given: Siva
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- family: Laryea
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given: Haziel A.
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- family: Murray
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given: Kennan B.
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- family: Thornberry
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given: Jutta S.
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- family: Joseph
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given: Jill G.
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da: '2023-09-28'
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doi: 10.1186/1471-2458-7-233
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eissn: 1471-2458
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files: []
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journal: BMC PUBLIC HEALTH
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keywords-plus: 'COMMUNITY-BASED RESEARCH; AFRICAN-AMERICAN; CLINICAL-TRIALS; HEALTH;
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PARTICIPATION; BARRIERS; ISSUES'
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language: English
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month: SEP 6
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number-of-cited-references: '40'
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papis_id: 5a61bebd51a8674697c5dc7fc13ea686
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ref: Elkhorazaty2007recruitmentretention
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times-cited: '88'
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title: Recruitment and retention of low-income minority women in a behavioral intervention
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to reduce smoking, depression, and intimate partner violence during pregnancy
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type: article
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unique-id: WOS:000250503000001
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usage-count-last-180-days: '1'
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usage-count-since-2013: '27'
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volume: '7'
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web-of-science-categories: Public, Environmental \& Occupational Health
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year: '2007'
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