abstract: 'Previous studies have reported a considerable employment disadvantage among people with epilepsy. In a cohort of men and women who had experienced a single seizure or had early epilepsy at study entry we explored employment status and social mobility over 4 years and investigated whether employment outcomes were more disadvantageous for certain social groups. Analyses were based on 350 individuals of working age identified via the UK Multicentre Study of Early Epilepsy and Single Seizures. Employment rates were calculated for the cohort and general population. Employment trajectories over 4 years were explored according to occupational social class. The relative risk of employment was calculated by clinical features of seizures and social class. Individuals with single seizures or early epilepsy had significantly lower employment rates than the general population at study entry, and 2- and 4-year follow-up. Employment rates of men and women in the cohort did not differ significantly. Although little social class mobility occurred during follow-up, there was evidence of some downward mobility between first seizure(s) and study entry. In the fully adjusted model, nonemployment was predicted at all time points by having fair/poor self-rated health and experiencing four or more seizures. We observed that some individuals continued to work in hazardous occupations or drive professionally within a year of experiencing seizure(s). People who have recently experienced a single seizure or who have early epilepsy are exposed to substantial employment disadvantage. Greater efforts are necessary to help these people return to work and stay employed.' affiliation: 'Holland, P (Corresponding Author), Univ Lancaster, Div Hlth Res, Bowland Tower E, Lancaster LA1 4YK, England. Holland, Paula; Whitehead, Margaret; Jacoby, Ann, Univ Liverpool, Div Publ Hlth, Liverpool L69 3BX, Merseyside, England. Lane, Steven, Univ Liverpool, Ctr Med Stat \& Hlth Evaluat, Liverpool L69 3BX, Merseyside, England. Marson, Anthony G., Univ Liverpool, Div Neurosci, Liverpool L69 3BX, Merseyside, England.' author: Holland, Paula and Lane, Steven and Whitehead, Margaret and Marson, Anthony G. and Jacoby, Ann author-email: p.j.holland@lancaster.ac.uk author_list: - family: Holland given: Paula - family: Lane given: Steven - family: Whitehead given: Margaret - family: Marson given: Anthony G. - family: Jacoby given: Ann da: '2023-09-28' doi: 10.1111/j.1528-1167.2008.01819.x files: [] issn: 0013-9580 journal: EPILEPSIA keywords: 'New-onset epilepsy; Single seizures; Employment; Social mobility; Longitudinal' keywords-plus: 'QUALITY-OF-LIFE; WELL-CONTROLLED EPILEPSY; EMPLOYMENT STATUS; SINGLE SEIZURES; ILL HEALTH; PEOPLE; UNEMPLOYMENT; STIGMA; ADULT; MOBILITY' language: English month: MAY number: '5' number-of-cited-references: '37' orcid-numbers: 'Marson, Anthony/0000-0002-6861-8806 Holland, Paula/0000-0002-8324-9957' pages: 1030-1039 papis_id: 39a58af4ccea65fb13d8c7cad825120c ref: Holland2009labormarket researcherid-numbers: 'Marson, Anthony/AAW-9776-2020 ' times-cited: '30' title: 'Labor market participation following onset of seizures and early epilepsy: Findings from a UK cohort' type: article unique-id: WOS:000265770000009 usage-count-last-180-days: '1' usage-count-since-2013: '7' volume: '50' web-of-science-categories: Clinical Neurology year: '2009'