abstract: 'Background: Disproportionate risks of COVID-19 in congregate care facilities including long-term care homes, retirement homes, and shelters both affect and are affected by SARS-CoV-2 infections among facility staff. In cities across Canada, there has been a consistent trend of geographic clustering of COVID-19 cases. However, there is limited information on how COVID-19 among facility staff reflects urban neighborhood disparities, particularly when stratified by the social and structural determinants of community-level transmission. Objective: This study aimed to compare the concentration of cumulative cases by geography and social and structural determinants across 3 mutually exclusive subgroups in the Greater Toronto Area (population: 7.1 million): community, facility staff, and health care workers (HCWs) in other settings.Methods: We conducted a retrospective, observational study using surveillance data on laboratory-confirmed COVID-19 cases (January 23 to December 13, 2020; prior to vaccination rollout). We derived neighborhood-level social and structural determinants from census data and generated Lorenz curves, Gini coefficients, and the Hoover index to visualize and quantify inequalities in cases.Results: The hardest-hit neighborhoods (comprising 20\% of the population) accounted for 53.87\% (44,937/83,419) of community cases, 48.59\% (2356/4849) of facility staff cases, and 42.34\% (1669/3942) of other HCW cases. Compared with other HCWs, cases among facility staff reflected the distribution of community cases more closely. Cases among facility staff reflected greater social and structural inequalities (larger Gini coefficients) than those of other HCWs across all determinants. Facility staff cases were also more likely than community cases to be concentrated in lower-income neighborhoods (Gini 0.24, 95\% CI 0.15-0.38 vs 0.14, 95\% CI 0.08-0.21) with a higher household density (Gini 0.23, 95\% CI 0.17-0.29 vs 0.17, 95\% CI 0.12-0.22) and with a greater proportion working in other essential services (Gini 0.29, 95\% CI 0.21-0.40 vs 0.22, 95\% CI 0.17-0.28).Conclusions: COVID-19 cases among facility staff largely reflect neighborhood-level heterogeneity and disparities, even more so than cases among other HCWs. The findings signal the importance of interventions prioritized and tailored to the home geographies of facility staff in addition to workplace measures, including prioritization and reach of vaccination at home (neighborhood level) and at work.' affiliation: 'Mishra, S (Corresponding Author), Univ Toronto, Dept Med, Div Infect Dis, Toronto, ON, Canada. Mishra, S (Corresponding Author), Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada. Mishra, S (Corresponding Author), St Michaels Hosp, Unity Hlth Toronto, Room 315,209 Victoria St, Toronto, ON M5B 1T8, Canada. Ma, Huiting; Yiu, Kristy C. Y.; Fahim, Christine; Moloney, Gary; Darvin, Dariya; Landsman, David; Straus, Sharon; Mishra, Sharmistha, St Michaels Hosp, Unity Hlth Toronto, Toronto, ON, Canada. Baral, Stefan D., Johns Hopkins Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA. Chan, Adrienne K.; Mishra, Sharmistha, Univ Toronto, Dept Med, Div Infect Dis, Toronto, ON, Canada. Chan, Adrienne K.; Mishra, Sharmistha, Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada. Chan, Adrienne K., Univ Toronto, Div Infect Dis, Sunnybrook Hlth Sci, Toronto, ON, Canada. Chan, Adrienne K.; Mishra, Sharmistha, Univ Toronto, Inst Hlth Policy Management \& Evaluat, Toronto, ON, Canada. Straus, Sharon, Univ Toronto, Dept Med, Toronto, ON, Canada. Mishra, Sharmistha, St Michaels Hosp, Unity Hlth Toronto, Room 315,209 Victoria St, Toronto, ON M5B 1T8, Canada.' article-number: e34927 author: Ma, Huiting and Yiu, Kristy C. Y. and Baral, Stefan D. and Fahim, Christine and Moloney, Gary and Darvin, Dariya and Landsman, David and Chan, Adrienne K. and Straus, Sharon and Mishra, Sharmistha author-email: sharmistha.mishra@utoronto.ca author_list: - family: Ma given: Huiting - family: Yiu given: Kristy C. Y. - family: Baral given: Stefan D. - family: Fahim given: Christine - family: Moloney given: Gary - family: Darvin given: Dariya - family: Landsman given: David - family: Chan given: Adrienne K. - family: Straus given: Sharon - family: Mishra given: Sharmistha da: '2023-09-28' doi: 10.2196/34927 files: [] issn: 2369-2960 journal: JMIR PUBLIC HEALTH AND SURVEILLANCE keywords: 'long-term care; nursing home; staff; essential worker; retirement home; shelter; congregate living; COVID-19; observational; risk; transmission; elderly; older adults; retirement; nurse; health care worker; congregate; trend; geography; Canada; Toronto' keywords-plus: TRANSMISSION; SARS-COV-2; CANADA; HEALTH; INDEX; HOMES language: English month: OCT number: '10' number-of-cited-references: '46' orcid-numbers: 'Yiu, Kristy/0000-0002-7378-9773 Mishra, Sharmistha/0000-0001-8492-5470 Ma, Huiting/0000-0003-1910-5614' papis_id: c6d18de5acac86572d58b0f5a1dd89fc ref: Ma2022covid19cases times-cited: '1' title: 'COVID-19 Cases Among Congregate Care Facility Staff by Neighborhood of Residence and Social and Structural Determinants: Observational Study' type: article unique-id: WOS:000867515600003 usage-count-last-180-days: '1' usage-count-since-2013: '2' volume: '8' web-of-science-categories: Public, Environmental \& Occupational Health year: '2022'