abstract: 'Lay Summary Ask-Advise-Connect (AAC) simplifies and streamlines the process of asking patients about their smoking status, advising smokers to quit, and connecting patients through the electronic health record with free, evidence-based tobacco cessation treatment offered by state Quitlines. This study is the first to evaluate perceptions of AAC among clinic leadership and staff. After an 18-month implementation of AAC at a clinic serving mostly low-income Latinos and Latinas, clinic staff (e.g., medical assistants) and leaders were interviewed. Respondents reported that AAC streamlined their efforts to get patients to quit smoking, was easy to carry out, and fit well into the clinic flow. Staff wanted to keep AAC as the standard of care and made suggestions to improve how AAC works. They reported positive feedback from patients. In addition, a similar proportion of smokers enrolled in Quitline treatment as in other AAC trials. Thus, AAC worked well for patients and clinic staff. Having AAC in other clinics could improve enrollment in evidence-based smoking cessation treatment, facilitate successful smoking cessation among low-income primary care patients, and reduce burden on healthcare providers. This study is the first to evaluate clinic staff and leadership perceptions of Ask-Advise-Connect (AAC), which seamlessly connects smokers in healthcare settings with evidence-based tobacco treatment using the EHR. Clinic staff and leadership reported enthusiasm for AAC implementation, as the procedure streamlined the clinic''s smoking cessation efforts, fit well into clinic flow, and was beneficial to patients. Ask-Advise-Connect (AAC) efficiently links smokers in healthcare settings with evidence-based Quitline-delivered tobacco treatment through training clinic staff to systematically ask patients about smoking status, advise smokers to quit, and connect patients with state Quitlines using the electronic health record. This study utilized a mixed-methods approach, guided by the RE-AIM framework, to evaluate the implementation of AAC in a Federally Qualified Health Center (FQHC). AAC was implemented for 18 months at a FQHC serving primarily low-socioeconomic status (SES) Latinos and Latinas. Results are presented within the RE-AIM conceptual framework which includes dimensions of reach, effectiveness, adoption, implementation, and maintenance. Quantitative patient-level outcomes of reach, effectiveness, and Impact were calculated. Post-implementation, in-depth interviews were conducted with clinic leadership and staff (N = 9) to gather perceptions and inform future implementation efforts. During the implementation period, 12.0\% of GNHC patients who reported current smoking both agreed to have their information sent to the Quitline and were successfully contacted by the Quitline (Reach), 94.8\% of patients who spoke with the Quitline enrolled in treatment (Effectiveness), and 11.4\% of all identified smokers enrolled in Quitline treatment (Impact). In post-implementation interviews assessing RE-AIM dimensions, clinic staff and leadership identified facilitators and advantages of AAC and reported that AAC was easy to learn and implement, streamlined existing procedures, and had a positive impact on patients. Staff and leadership reported enthusiasm about AAC implementation and believed AAC fit well in the clinic. Staff were interested in AAC becoming the standard of care and made suggestions for future implementation. Clinic staff at a FQHC serving primarily low-SES Latinos and Latinas viewed the ACC implementation process positively. Findings have implications for streamlining clinical smoking cessation procedures and the potential to reduce tobacco-related disparities.' affiliation: 'Fennell, BS (Corresponding Author), H Lee Moffitt Canc Ctr \& Res Inst, Dept Hlth Outcomes \& Behav, Tampa, FL 33612 USA. Shorey Fennell, Bethany; Cottrell-Daniels, Cherell; Vidrine, Damon J.; Vidrine, Jennifer, I, H Lee Moffitt Canc Ctr \& Res Inst, Dept Hlth Outcomes \& Behav, Tampa, FL 33612 USA. Hoover, Diana Stewart, Hoover Editing, Asheville, NC USA. Spears, Claire A., Georgia State Univ, Sch Publ Hlth, Div Hlth Promot \& Behav, Atlanta, GA USA. Nguyen, Nga, Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX USA. Pineiro, Barbara, Univ Autonoma Barcelona, Ctr Estudis Demograf, Catalonia 08193, Spain. McNeill, Lorna H., Univ Texas MD Anderson Canc Ctr, Dept Hlth Dispar Res, Houston, TX USA. Wetter, David W., Univ Utah, Huntsman Canc Inst, Ctr Hlth Outcomes \& Populat Equ, Dept Populat Hlth Sci, Salt Lake City, UT USA.' author: Shorey Fennell, Bethany and Cottrell-Daniels, Cherell and Hoover, Diana Stewart and Spears, Claire A. and Nguyen, Nga and Pineiro, Barbara and McNeill, Lorna H. and Wetter, David W. and Vidrine, Damon J. and Vidrine I, Jennifer author-email: Bethany.ShoreyFennell@moffitt.org author_list: - family: Shorey Fennell given: Bethany - family: Cottrell-Daniels given: Cherell - family: Hoover given: Diana Stewart - family: Spears given: Claire A. - family: Nguyen given: Nga - family: Pineiro given: Barbara - family: McNeill given: Lorna H. - family: Wetter given: David W. - family: Vidrine given: Damon J. - family: Vidrine I given: Jennifer da: '2023-09-28' doi: 10.1093/tbm/ibad007 earlyaccessdate: MAR 2023 eissn: 1613-9860 files: [] issn: 1869-6716 journal: TRANSLATIONAL BEHAVIORAL MEDICINE keywords: 'Implementation; Qualitative; Smoking cessation; Quitline; Latinos; Latinas; low-SES' keywords-plus: 'SMOKING-CESSATION; CIGARETTE-SMOKING; UNITED-STATES; PRIMARY-CARE; TOBACCO; INTERVENTION; SMOKERS; IMPACT; DISPARITIES; QUITLINES' language: English month: AUG 11 number: '8' number-of-cited-references: '56' orcid-numbers: Shorey Fennell, Bethany/0000-0003-2188-6544 pages: 551-560 papis_id: 2c39f272764b307cfa51e9640e92a9f1 ref: Shoreyfennell2023implementationaskadv times-cited: '0' title: 'The implementation of ask-advise-connect in a federally qualified health center: a mixed methods evaluation using the re-aim framework' type: article unique-id: WOS:000961071600001 usage-count-last-180-days: '3' usage-count-since-2013: '3' volume: '13' web-of-science-categories: Public, Environmental \& Occupational Health year: '2023'