abstract: 'Underuse-the failure to use effective and affordable medical interventions-is common and responsible for substantial suffering, disability, and loss of life worldwide. Underuse occurs at every point along the treatment continuum, from populations lacking access to health care to inadequate supply of medical resources and labour, slow or partial uptake of innovations, and patients not accessing or declining them. The extent of underuse for different interventions varies by country, and is documented in countries of high, middle, and low-income, and across different types of health-care systems, payment models, and health services. Most research into underuse has focused on measuring solutions to the problem, with considerably less attention paid to its global prevalence or its consequences for patients and populations. Although focused effort and resources can overcome specific underuse problems, comparatively little is spent on work to better understand and overcome the barriers to improved uptake of effective interventions, and methods to make them affordable.' affiliation: 'Glasziou, P (Corresponding Author), Bond Univ, Ctr Res Evidence Based Practice, Gold Coast, Qld 4229, Australia. Glasziou, Paul, Bond Univ, Ctr Res Evidence Based Practice, Robina, Qld, Australia. Straus, Sharon, Univ Toronto, St Michaels Hosp, Li Ka Shing Knowledge Inst, Dept Med, Toronto, ON, Canada. Brownlee, Shannon; Saini, Vikas, Lown Inst, Brookline, MA USA. Trevena, Lyndal, Univ Sydney, Sch Publ Hlth, Discipline Gen Practice, Sydney, NSW, Australia. Elshaug, Adam G., Univ Sydney, Sch Publ Hlth, Menzies Ctr Hlth Policy, Sydney, NSW, Australia. Dans, Leonila, Univ Philippines Manila, Manila, Philippines. Guyatt, Gordon, McMaster Univ, Dept Clin Epidemiol \& Biostat, Hamilton, ON, Canada. Janett, Robert, Harvard Clin \& Translat Sci Ctr, Boston, MA USA.' author: Glasziou, Paul and Straus, Sharon and Brownlee, Shannon and Trevena, Lyndal and Dans, Leonila and Guyatt, Gordon and Elshaug, Adam G. and Janett, Robert and Saini, Vikas author-email: paul\_glasziou@bond.edu.au author_list: - family: Glasziou given: Paul - family: Straus given: Sharon - family: Brownlee given: Shannon - family: Trevena given: Lyndal - family: Dans given: Leonila - family: Guyatt given: Gordon - family: Elshaug given: Adam G. - family: Janett given: Robert - family: Saini given: Vikas da: '2023-09-28' doi: 10.1016/S0140-6736(16)30946-1 eissn: 1474-547X files: [] issn: 0140-6736 journal: LANCET keywords-plus: 'MIDDLE-INCOME COUNTRIES; ATRIAL-FIBRILLATION; CARE; GUIDELINES; MORTALITY; QUALITY; INTERVENTION; PREVENTION; STRATEGY; DELIVERY' language: English month: JUL 8 number: '10090' number-of-cited-references: '56' orcid-numbers: 'Glasziou, Paul/0000-0001-7564-073X Elshaug, Adam/0000-0002-4939-5379' pages: 169-177 papis_id: 3996895aca1b7ffd14bdff7c6140197e ref: Glasziou2017evidenceunderuse researcherid-numbers: 'Elshaug, Adam G/A-5714-2008 Glasziou, Paul/A-7832-2008 ' times-cited: '131' title: Evidence for underuse of effective medical services around the world type: article unique-id: WOS:000404976600034 usage-count-last-180-days: '2' usage-count-since-2013: '21' volume: '390' web-of-science-categories: Medicine, General \& Internal year: '2017'