abstract: 'Background Transportation vulnerability (defined as lack of personal/public transportation access) is particularly prevalent in areas with high racial/ethnic segregation where communities typically lack proximity to quality education, jobs, healthy food, playgrounds, and medical care. Prior research has shown an association between residential segregation and youth cardiovascular health, although little work has examined the effects of transportation vulnerability on this relationship. Methods Longitudinal mixed methods were used to compare the effects of transportation vulnerability on the association between changes in exposure to residential segregation (defined as the uneven geographic distribution of minorities) and five cardiovascular health outcomes across sex in minority youth for up to four consecutive years of participation in an afterschool fitness program during 2010-2018 (n = 2742; Miami-Dade County, Florida, US). Results After accounting for child race/ethnicity, age, year, and poverty, girls with high transportation vulnerability and reduced exposure to segregation (vs. increased or no change in segregation) showed the most improvements across all outcomes, including body mass index percentile (26\% (95\% CI 23.84, 28.30)), sum of skinfold thicknesses (18\% (95\% CI 14.90, 20.46)), run time (17\% (95\% CI 14.88, 18.64)), systolic blood pressure percentile (15\% (95\% CI 11.96, 17.08)), and diastolic blood pressure percentile (12\% (95\% CI 9.09, 14.61)). Conclusion Transportation inequities related to concentrated racial/ethnic segregation may be an important factor in reducing disparities in youth cardiovascular health, particularly among girls. These study findings provide important longitudinal evidence in support of health interventions to reduce transportation vulnerability for racial/ethnic minority youth in underserved areas.' affiliation: 'D''Agostino, EM (Corresponding Author), Duke Univ, Dept Family Med \& Community Hlth, Sch Med, 2200 W Main St,Off 623,6th Fl, Durham, NC 27705 USA. D''Agostino, EM (Corresponding Author), Miami Dade Cty Dept Pk Recreat \& Open Spaces, 275 NW 2nd St, Miami, FL 33128 USA. D''Agostino, Emily M., Duke Univ, Dept Family Med \& Community Hlth, Sch Med, 2200 W Main St,Off 623,6th Fl, Durham, NC 27705 USA. D''Agostino, Emily M.; Patel, Hersila H.; Hansen, Eric, Miami Dade Cty Dept Pk Recreat \& Open Spaces, 275 NW 2nd St, Miami, FL 33128 USA. Mathew, M. Sunil; Messiah, Sarah E., Univ Miami, Miller Sch Med, Dept Pediat, 1601 NW 12th Ave, Miami, FL 33136 USA. Mathew, M. Sunil; Messiah, Sarah E., Univ Texas Hlth Sci Ctr, Sch Publ Hlth, Dallas, TX USA. Messiah, Sarah E., Childrens Hlth Syst Texas, Ctr Pediat Populat Hlth, Dallas, TX USA. Messiah, Sarah E., UTHlth Sci Ctr Sch Publ Hlth, Dallas, TX USA.' author: D'Agostino, Emily M. and Patel, Hersila H. and Hansen, Eric and Mathew, M. Sunil and Messiah, Sarah E. author-email: emily.m.dagostino@duke.edu author_list: - family: D'Agostino given: Emily M. - family: Patel given: Hersila H. - family: Hansen given: Eric - family: Mathew given: M. Sunil - family: Messiah given: Sarah E. da: '2023-09-28' doi: 10.1007/s40615-020-00821-8 earlyaccessdate: SEP 2020 eissn: 2196-8837 files: [] issn: 2197-3792 journal: JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES keywords: 'Cardiovascular health; Fitness; Health disparities; Racial; ethnic segregation; Transportation vulnerability; Youth' keywords-plus: 'PHYSICAL-ACTIVITY; RESIDENTIAL SEGREGATION; RACIAL DISPARITIES; BUILT ENVIRONMENT; LAND-USE; NEIGHBORHOOD; RISK; BEHAVIOR; OBESITY; FITNESS' language: English month: JUN number: '3' number-of-cited-references: '75' orcid-numbers: 'D''Agostino, DrPH, MS, MEd, MA, Emily/0000-0003-0468-4836 Messiah, Sarah/0000-0001-6685-2175' pages: 618-629 papis_id: 58e8ff313c9231d5ac77334bc0e7110e ref: Dagostino2021longitudinaleffects researcherid-numbers: 'Hansen, Eric/JEF-6566-2023 D''Agostino, Emily/IUO-1837-2023 ' times-cited: '8' title: Longitudinal Effects of Transportation Vulnerability on the Association Between Racial/Ethnic Segregation and Youth Cardiovascular Health type: article unique-id: WOS:000565504400001 usage-count-last-180-days: '0' usage-count-since-2013: '8' volume: '8' web-of-science-categories: Public, Environmental \& Occupational Health year: '2021'