abstract: 'Background: Tuberculosis (TB) is a disease that disproportionately affects the poor. The World Health Organization lists economic factors as one of main barriers to tuberculosis management. Aims: This study aimed to estimate the household total catastrophic cost of TB and its determinants among newly diag-nosed Egyptian tuberculous patients. Methods: This was a cohort prospective study covering 257 TB patients registered in 2019. The patients were followed up bi-monthly until the end of the treatment regimen (4 visits). A standardized questionnaire published by the poverty sub-working group of the Stop TB Partnership was used after minor modification. The following costs were measured: pre-diagnosis, direct and indirect, guardian and coping, as well as annual household income. Catastrophic cost (direct plus indirect) was considered if the total cost of TB treatment exceeded 20\% of the household''s annual income. Sensitivity analyses were conducted using different thresholds. Results: The incidence of household total catastrophic cost was 24.1\%. The mean total cost of TB treatment was US\$ 198. Over 50\% of the total direct cost was incurred during the pre-diagnosis period. After adjustment for other determinant variables using multivariable logistic regression, we found that age < 30 years, living in a house with crowding index > 2, poverty and coping were more likely to cause higher total catastrophic cost. Conclusions: Catastrophic cost was experienced by 1 out of every 4 new TB patients. As the main cost drivers were pover-ty and coping, the Ministry of Health and Population should be collaborated with Ministry of Finance and NGOs to put a plan of social protection system for poor families with TB patients.' affiliation: 'Gadallah, M (Corresponding Author), Ain Shams Univ, Dept Community Med, Fac Med, Cairo, Egypt. Gadallah, Mohsen; Rady, Mervat, Ain Shams Univ, Dept Community Med, Fac Med, Cairo, Egypt. Amin, Wagdy, Minist Hlth \& Populat, Chest Dept, Cairo, Egypt.' author: Gadallah, Mohsen and Amin, Wagdy and Rady, Mervat author-email: mohsengadallah@gmail.com author_list: - family: Gadallah given: Mohsen - family: Amin given: Wagdy - family: Rady given: Mervat da: '2023-09-28' doi: 10.26719/emhj.22.049 eissn: 1687-1634 files: [] issn: 1020-3397 journal: EASTERN MEDITERRANEAN HEALTH JOURNAL keywords: catastrophic cost; tuberculosis; economic burden; cohort study; Egypt keywords-plus: ECONOMIC BURDEN; DETERMINANTS; COUNTRIES; ILLNESS; CARE language: English month: JUL number: '7' number-of-cited-references: '24' pages: 489-497 papis_id: ade1aa6731344d9502fadf88fba99509 ref: Gadallah2022householdcatastrophi times-cited: '1' title: 'Household catastrophic total cost due to tuberculosis in Egypt: incidence, cost drivers and policy implication' type: article unique-id: WOS:000835888900004 usage-count-last-180-days: '0' usage-count-since-2013: '0' volume: '28' web-of-science-categories: 'Health Care Sciences \& Services; Health Policy \& Services; Public, Environmental \& Occupational Health' year: '2022'