abstract: 'Background: Patient navigation programs have been launched nationwide in an attempt to reduce racial/ethnic and socio-demographic disparities in cancer care, but few have evaluated outcomes in the prostate cancer setting. The National Cancer Institute-funded Chicago Patient Navigation Research Program (C-PNRP) aims to implement and evaluate the efficacy of a patient navigation intervention for predominantly low-income minority patients with an abnormal prostate cancer screening test at a Veterans Affairs (VA) hospital in Chicago. Methods/Design: From 2006 through 2010, C-PNRP implemented a quasi-experimental intervention whereby trained social worker and lay health navigators worked with veterans with an abnormal prostate screen to proactively identify and resolve personal and systems barriers to care. Men were enrolled at a VA urology clinic and were selected to receive navigated versus usual care based on clinic day. Patient navigators performed activities to facilitate timely follow-up such as appointment reminders, transportation coordination, cancer education, scheduling assistance, and social support as needed. Primary outcome measures included time (days) from abnormal screening to diagnosis and time from diagnosis to treatment initiation. Secondary outcomes included psychosocial and demographic predictors of non-compliance and patient satisfaction. Dates of screening, follow-up visits, and treatment were obtained through chart audit, and questionnaires were administered at baseline, after diagnosis, and after treatment initiation. At the VA, 546 patients were enrolled in the study (245 in the navigated arm, 245 in the records-based control arm, and 56 in a subsample of surveyed control subjects). Discussion: Given increasing concerns about balancing better health outcomes with lower costs, careful examination of interventions aimed at reducing healthcare disparities attain critical importance. While analysis of the C-PNRP data is underway, the design of this patient navigation intervention will inform other patient navigation programs addressing strategies to improve prostate cancer outcomes among vulnerable populations.' affiliation: 'Simon, MA (Corresponding Author), Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Chicago, IL 60611 USA. Nonzee, Narissa J.; McKoy, June M.; Rademaker, Alfred W.; Byer, Peter; Liu, Dachao; Simon, Melissa A., Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Chicago, IL 60611 USA. Nonzee, Narissa J., Jesse Brown VA Med Ctr, Chicago, IL USA. McKoy, June M., Northwestern Univ, Feinberg Sch Med, Div Gen Internal Med \& Geriatr, Dept Med, Chicago, IL 60611 USA. McKoy, June M.; Rademaker, Alfred W.; Liu, Dachao; Simon, Melissa A., Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA. Thanh Ha Luu; Samaras, Athena T.; Simon, Melissa A., Northwestern Univ, Feinberg Sch Med, Dept Obstet \& Gynecol, Chicago, IL 60611 USA. Richey, Elizabeth A., Dartmouth Coll, Geisel Sch Med, Hanover, NH 03755 USA. Panucci, Genna, Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA. Dong, XinQi, Rush Univ, Inst Hlth Aging, Chicago, IL 60612 USA.' article-number: '340' author: Nonzee, Narissa J. and McKoy, June M. and Rademaker, Alfred W. and Byer, Peter and Luu, Thanh Ha and Liu, Dachao and Richey, Elizabeth A. and Samaras, Athena T. and Panucci, Genna and Dong, XinQi and Simon, Melissa A. author-email: m-simon2@northwestern.edu author_list: - family: Nonzee given: Narissa J. - family: McKoy given: June M. - family: Rademaker given: Alfred W. - family: Byer given: Peter - family: Luu given: Thanh Ha - family: Liu given: Dachao - family: Richey given: Elizabeth A. - family: Samaras given: Athena T. - family: Panucci given: Genna - family: Dong given: XinQi - family: Simon given: Melissa A. da: '2023-09-28' doi: 10.1186/1472-6963-12-340 eissn: 1472-6963 files: [] journal: BMC HEALTH SERVICES RESEARCH keywords: Patient navigation; Prostate cancer; Cancer health disparities; Veterans keywords-plus: 'RELIABILITY-ANALYSIS; RANDOMIZED PROSTATE; MORTALITY; RACE; DIAGNOSIS; LITERACY; SATISFACTION; DISPARITIES; VALIDATION; ACCESS' language: English month: SEP 25 number-of-cited-references: '46' papis_id: 03ed09668c7baf8f3d6a78ca823f2c77 ref: Nonzee2012designprostate researcherid-numbers: 'MCKOY, JUNE/GRJ-5660-2022 Dong, Xin/IZQ-2213-2023 Dong, Xin/HSG-6425-2023' times-cited: '10' title: Design of a prostate cancer patient navigation intervention for a Veterans Affairs hospital type: Article unique-id: WOS:000311939100001 usage-count-last-180-days: '0' usage-count-since-2013: '15' volume: '12' web-of-science-categories: Health Care Sciences \& Services year: '2012'