abstract: 'Background: Patients with cystic fibrosis (CF) experience obstacles to

  employment, regardless of whether they have undergone lung

  transplantation (LTx). We investigated socioeconomic and clinical

  factors predicting long-term employment outcomes in CF patients

  receiving LTx.

  Methods: Data from the United Network for Organ Sharing registry were

  used to identify CF patients 18-59 years-old who received LTx between

  2000 and 2010 and survived greater than 5 years. Long-term employment

  status was determined by center-reported follow-up data on patients

  working for income, collected at the 5th transplant anniversary. After

  multiple imputation to complete missing data on covariates,

  multivariable logistic regression was used to identify associations

  between characteristics at or after LTx and long-term work

  participation.

  Results: There were 745 patients who met inclusion criteria and

  contributed employment data within 365 days of their 5th LTx

  anniversary. In this cohort, 48\% (358/745) were working for income 5

  years after LTx. Younger age, male gender, better pulmonary function

  attained post-transplant, pre-transplant work participation, and private

  health insurance (compared to government Medicaid or Medicare insurance)

  at the time of transplant predicted greater odds of post-transplant

  employment.

  Conclusions: Lack of work experience and reliance on government health

  insurance at the time of transplant predict lower long-term work

  participation among LTx recipients with CF. By contrast, long-term

  employment outcomes were not negatively affected by comorbidities at or

  after transplantation in this cohort. Despite resolving some

  physiological obstacles to employment in patients with CF, LTx may

  introduce new socioeconomic barriers to employment. (C) 2016 European

  Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.'
affiliation: 'Krivchenia, K (Corresponding Author), Ohio State Univ, Coll Med, Dept
  Pediat, 370 W 9th Ave, Columbus, OH 43210 USA.

  Krivchenia, K (Corresponding Author), Nationwide Childrens Hosp, Ctr Epidemiol Study
  Organ Failure \& Transplantat, 700 Childrens Dr, Columbus, OH 43205 USA.

  Krivchenia, K (Corresponding Author), Nationwide Childrens Hosp, Sect Pulm Med,
  700 Childrens Dr, Columbus, OH 43205 USA.

  Krivchenia, Katelyn; Hayes, Don, Jr.; Tumin, Dmitry, Ohio State Univ, Coll Med,
  Dept Pediat, 370 W 9th Ave, Columbus, OH 43210 USA.

  Tobias, Joseph D., Ohio State Univ, Coll Med, Anesthesiol \& Pain Med, 370 W 9th
  Ave, Columbus, OH 43210 USA.

  Hayes, Don, Jr., Ohio State Univ, Coll Med, Internal Med, 370 W 9th Ave, Columbus,
  OH 43210 USA.

  Hayes, Don, Jr., Ohio State Univ, Coll Med, Surg, 370 W 9th Ave, Columbus, OH 43210
  USA.

  Krivchenia, Katelyn; Hayes, Don, Jr.; Tobias, Joseph D.; Tumin, Dmitry, Nationwide
  Childrens Hosp, Ctr Epidemiol Study Organ Failure \& Transplantat, 700 Childrens
  Dr, Columbus, OH 43205 USA.

  Tobias, Joseph D.; Tumin, Dmitry, Nationwide Childrens Hosp, Dept Anesthesiol \&
  Pain Med, 700 Childrens Dr, Columbus, OH 43205 USA.

  Krivchenia, Katelyn; Hayes, Don, Jr., Nationwide Childrens Hosp, Sect Pulm Med,
  700 Childrens Dr, Columbus, OH 43205 USA.'
author: Krivchenia, Katelyn and Hayes Jr., Don and Tobias, Joseph D. and Tumin, Dmitry
author-email: 'katelynicrivchenia@nationwidechildrens.org

  don.hayes@nationwidechildrens.org

  joseph.tobias@nationwidechildrens.org

  dmitry.tumin@nationwidechildrens.org'
author_list:
- family: Krivchenia
  given: Katelyn
- family: Hayes Jr.
  given: Don
- family: Tobias
  given: Joseph D.
- family: Tumin
  given: Dmitry
da: '2023-09-28'
doi: 10.1016/j.jcf.2016.07.007
eissn: 1873-5010
files: []
issn: 1569-1993
journal: JOURNAL OF CYSTIC FIBROSIS
keywords: Lung transplantation; Employment; Cystic fibrosis
keywords-plus: EMPLOYMENT; ADULTS; DISABILITY; RETURN
language: English
month: NOV
number: '6'
number-of-cited-references: '18'
orcid-numbers: Tumin, Dmitry/0000-0002-9180-7656
pages: 846-849
papis_id: 1b4a80a9e5ea14e1aaf703dae8ef4015
ref: Krivchenia2016longtermwork
researcherid-numbers: 'Tumin, Dmitry/AAG-6295-2021

  '
times-cited: '13'
title: Long-term work participation among cystic fibrosis patients undergoing lung
  transplantation
type: Article
unique-id: WOS:000390517700023
usage-count-last-180-days: '0'
usage-count-since-2013: '0'
volume: '15'
web-of-science-categories: Respiratory System
year: '2016'