abstract: 'Purpose of reviewThe burden of critical illness in low-income and middle-income countries (LMICs) is substantial. A better understanding of critical care outcomes is essential for improving critical care delivery in resource-limited settings. In this review, we provide an overview of recent literature reporting on critical care outcomes in LMICs. We discuss several barriers and potential solutions for a better understanding of critical care outcomes in LMICs.Recent findingsEpidemiologic studies show higher in-hospital mortality rates for critically ill patients in LMICs as compared with patients in high-income countries (HICs). Recent findings suggest that critical care interventions that are effective in HICs may not be effective and may even be harmful in LMICs. Little data on long-term and morbidity outcomes exist. Better outcomes measurement is beginning to emerge in LMICs through decision support tools that report process outcome measures, studies employing mobile health technologies with community health workers and the development of context-specific severity of illness scores.SummaryOutcomes from HICs cannot be reliably extrapolated to LMICs, so it is important to study outcomes for critically ill patients in LMICs. Specific challenges to achieving meaningful outcomes studies in LMICs include defining the critically ill population when few ICU beds exist, the resource-intensiveness of long-term follow-up, and the need for reliable severity of illness scores to interpret outcomes. Although much work remains to be done, examples of studies overcoming these challenges are beginning to emerge.' affiliation: 'Vukoja, M (Corresponding Author), Inst Pulm Dis Vojvodina, Put Dr Goldmana 4, Sremska Kamenica 21204, Serbia. Vukoja, Marija, Inst Pulm Dis Vojvodina, Put Dr Goldmana 4, Sremska Kamenica 21204, Serbia. Vukoja, Marija, Univ Novi Sad, Fac Med, Novi Sad, Serbia. Riviello, Elisabeth D., Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Pulm Crit Care \& Sleep Med, Boston, MA USA. Schultz, Marcus J., Mahidol Univ, Mahidol Oxford Trop Med Res Unit MORU, Bangkok, Thailand. Schultz, Marcus J., Acad Med Ctr, Dept Intens Care, Amsterdam, Netherlands. Schultz, Marcus J., Acad Med Ctr, LEICA, Amsterdam, Netherlands.' author: Vukoja, Marija and Riviello, Elisabeth D. and Schultz, Marcus J. author-email: kojicic.marija@gmail.com author_list: - family: Vukoja given: Marija - family: Riviello given: Elisabeth D. - family: Schultz given: Marcus J. da: '2023-09-28' doi: 10.1097/MCC.0000000000000528 eissn: 1531-7072 files: [] issn: 1070-5295 journal: CURRENT OPINION IN CRITICAL CARE keywords: 'clinical trials; critical care; intensive care; low-income and middle-income countries; outcomes; resource-limited settings' keywords-plus: 'RESPIRATORY-DISTRESS-SYNDROME; LOW-INCOME COUNTRIES; LOW-MIDDLE-INCOME; INTENSIVE-CARE; ANTIMICROBIAL RESISTANCE; SEPSIS; MORTALITY; UNITS; MULTICENTER; AFRICA' language: English month: OCT number: '5' number-of-cited-references: '55' orcid-numbers: 'Schultz, Marcus/0000-0003-3969-7792 Vukoja, Marija/0000-0001-9560-3653 Riviello, Elisabeth/0000-0002-9443-3928' pages: 421-427 papis_id: eade8e395948472ac3b1203ac1eb5b20 ref: Vukoja2018criticalcare researcherid-numbers: 'Schultz, Marcus/AAB-6379-2021 Vukoja, Marija/AAA-5850-2020 ' tags: - review times-cited: '27' title: Critical care outcomes in resource-limited settings type: Review unique-id: WOS:000456316000015 usage-count-last-180-days: '1' usage-count-since-2013: '4' volume: '24' web-of-science-categories: Critical Care Medicine year: '2018'