abstract: 'There is considerable scientific and policy interest in reducing socioeconomic and racial/ethnic disparities in healthcare and health status. Currently, much of the policy focus around reducing health disparities has been geared toward improving access, coverage, quality, and the intensity of healthcare. However, health is more a function of lifestyles linked to living and working conditions than of healthcare. Accordingly, effective efforts to improve health and reduce gaps in health need to pay greater attention to addressing the social determinants of health within and outside of the healthcare system. This article highlights research evidence documenting that tackling the social determinants of health can lead to reductions in health disparities. It focuses both on interventions within the healthcare system that address some of the social determinants of health and on interventions in upstream factors such as housing, neighborhood conditions, and increased socioeconomic status that can lead to improvements in health. The studies reviewed highlight the importance of systematic evaluation of social and economic policies that might have health consequences and the need for policy makers, healthcare providers, and leaders across multiple sectors of society to apply currently available knowledge to improve the underlying conditions that impact the health of populations.' affiliation: 'Williams, DR (Corresponding Author), Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev \& Hlth, 677 Huntington Ave,6th Floor, Boston, MA 02115 USA. Williams, David R.; Costa, Manuela V.; Odunlami, Adebola O., Harvard Univ, Sch Publ Hlth, Dept Soc Human Dev \& Hlth, Boston, MA 02115 USA. Mohammed, Selina A., Univ Washington, Nursing Program, Bothell, WA USA. Williams, David R., Harvard Univ, Dept African \& African Amer Studies, Cambridge, MA 02138 USA. Williams, David R., Harvard Univ, Dept Sociol, Cambridge, MA 02138 USA.' author: Williams, David R. and Costa, Manuela V. and Odunlami, Adebola O. and Mohammed, Selina A. author-email: dwilliam@hsph.harvard.edu author_list: - family: Williams given: David R. - family: Costa given: Manuela V. - family: Odunlami given: Adebola O. - family: Mohammed given: Selina A. da: '2023-09-28' eissn: 1550-5022 files: [] issn: 1078-4659 journal: JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE keywords: healthcare; interventions; racial disparities; socioeconomic disparities keywords-plus: 'EARLY START PROGRAM; LOW-INCOME; RANDOMIZED-TRIAL; PRIMARY-CARE; ENVIRONMENT; CHILDREN; POVERTY; PARENTS; IMPACT; POLICY' language: English month: NOV number: S number-of-cited-references: '45' pages: S8-S17 papis_id: 04014534e17155890920d6b2b2ebbb4c ref: Williams2008movingupstream researcherid-numbers: Williams, David/HKN-3732-2023 times-cited: '305' title: 'Moving Upstream: How Interventions That Address the Social Determinants of Health Can Improve Health and Reduce Disparities' type: Article unique-id: WOS:000260467200004 usage-count-last-180-days: '0' usage-count-since-2013: '64' web-of-science-categories: Public, Environmental \& Occupational Health year: '2008'