abstract: 'Background Maternal morbidity and mortality related to infection is an international public health concern, but detection and assessment is often difficult as part of routine maternity care in many low- and middle-income countries due to lack of easily accessible diagnostics. Front-line healthcare providers are key for the early identification and management of the unwell woman who may have infection. We sought to investigate the knowledge, attitudes, and perceptions of the use of screening tools to detect infectious maternal morbidity during and after pregnancy as part of routine antenatal and postnatal care. Enabling factors, barriers, and potential management options for the use of early warning scores were explored. Methods Key informant interviews (n = 10) and two focus group discussions (n = 14) were conducted with healthcare providers and managers (total = 24) working in one large tertiary public hospital in Blantyre, Malawi. Transcribed interviews were coded by topic and then grouped into categories. Thematic framework analysis was undertaken to identify emerging themes. Results Most healthcare providers are aware of the importance of the early detection of infection and would seek to better identify women with infection if resources were available to do so. In current practice, an early warning score was used in the high dependency unit only. Routine screening was not in place in the antenatal or postnatal departments. Barriers to implementing routine screening included lack of trained staff and time, lack of thermometers, and difficulties with the interpretation of the early warning scores. A locally adapted early warning screening tool was considered an enabler to implementing routine screening for infectious morbidity. Local ownership and clinical leadership were considered essential for successful and sustainable implementation for clinical change. Conclusions Although healthcare providers considered infection during and after pregnancy and childbirth a danger sign and significant morbidity, standardised screening for infectious maternal morbidity was not part of routine antenatal or postnatal care. The establishment of such a service requires the availability of free and easy to access rapid diagnostic testing, training in interpretation of results, as well as affordable targeted treatment. The implementation of early warning scores and processes developed in high-income countries need careful consideration and validation when applied to women accessing care in low resource settings.' affiliation: 'McCauley, M (Corresponding Author), Liverpool Womens Hosp, Liverpool Womens NHS Fdn Trust, Crown St, Liverpool L8 7SS, Merseyside, England. Slezak, Emilia; Unger, Holger; McCauley, Mary, Univ Liverpool Liverpool Sch Trop Med, Ctr Maternal \& Newborn Hlth, Liverpool, Merseyside, England. Unger, Holger, Royal Darwin Hosp, Dept Obstet \& Gynaecol, Darwin, NT, Australia. Unger, Holger, Charles Darwin Univ, Menzies Sch Hlth Res, Darwin, NT, Australia. Gadama, Luis, Queen Elizabeth Hosp, Blantyre, Malawi. McCauley, Mary, Liverpool Womens Hosp, Liverpool Womens NHS Fdn Trust, Crown St, Liverpool L8 7SS, Merseyside, England.' article-number: '362' author: Slezak, Emilia and Unger, Holger and Gadama, Luis and McCauley, Mary author-email: mary.mccauley1@lwh.nhs.uk author_list: - family: Slezak given: Emilia - family: Unger given: Holger - family: Gadama given: Luis - family: McCauley given: Mary da: '2023-09-28' doi: 10.1186/s12884-022-04583-5 eissn: 1471-2393 files: [] journal: BMC PREGNANCY AND CHILDBIRTH keywords: 'Maternal morbidity; Infections; Early warning scores; Healthcare providers; Antenatal care; Postnatal care; SARS-CoV-2' keywords-plus: 'INFLAMMATORY RESPONSE SYNDROME; WARNING SYSTEM; IMPLEMENTATION; BARRIERS; MORTALITY; CRITERIA; OUTCOMES; IMPROVE; SEPSIS; EWS' language: English month: APR 26 number: '1' number-of-cited-references: '50' papis_id: ad7c99957940742ad1d87e68e2a54a21 ref: Slezak2022screeninginfectious times-cited: '1' title: 'Screening for infectious maternal morbidity-knowledge, attitudes and perceptions among healthcare providers and managers in Malawi: a qualitative study' type: Article unique-id: WOS:000787760200003 usage-count-last-180-days: '0' usage-count-since-2013: '1' volume: '22' web-of-science-categories: Obstetrics \& Gynecology year: '2022'