abstract: 'Background: Insurance coverage of tobacco cessation medications increases their use and reduces smoking prevalence in a population. However, uncertainty about the impact of this coverage on health care utilization and costs is a barrier to the broader adoption of this policy, especially by publicly funded state Medicaid insurance programs. Whether a publicly funded tobacco cessation benefit leads to decreased medical claims for tobacco-related diseases has not been studied. We examined the experience of Massachusetts, whose Medicaid program adopted comprehensive coverage of tobacco cessation medications in July 2006. Over 75,000 Medicaid subscribers used the benefit in the first 2.5 years. On the basis of earlier secondary survey work, it was estimated that smoking prevalence declined among subscribers by 10\% during this period. Methods and Findings: Using claims data, we compared the probability of hospitalization prior to use of the tobacco cessation pharmacotherapy benefit with the probability of hospitalization after benefit use among Massachusetts Medicaid beneficiaries, adjusting for demographics, comorbidities, seasonality, influenza cases, and the implementation of the statewide smoke-free air law using generalized estimating equations. Statistically significant annualized declines of 46\% (95\% confidence interval 2\%-70\%) and 49\% (95\% confidence interval 6\%-72\%) were observed in hospital admissions for acute myocardial infarction and other acute coronary heart disease diagnoses, respectively. There were no significant decreases in hospitalizations rates for respiratory diagnoses or seven other diagnostic groups evaluated. Conclusions: Among Massachusetts Medicaid subscribers, use of a comprehensive tobacco cessation pharmacotherapy benefit was associated with a significant decrease in claims for hospitalizations for acute myocardial infarction and acute coronary heart disease, but no significant change in hospital claims for other diagnoses. For low-income smokers, removing the barriers to the use of smoking cessation pharmacotherapy has the potential to decrease short-term utilization of hospital services.' affiliation: 'Land, T (Corresponding Author), Massachusetts Tobacco Cessat \& Prevent Program, Boston, MA USA. Land, Thomas; Paskowsky, Mark; Warner, Donna; Kwass, Jo-Ann; Keithly, Lois, Massachusetts Tobacco Cessat \& Prevent Program, Boston, MA USA. Rigotti, Nancy A.; Levy, Douglas E., Massachusetts Gen Hosp, Dept Med, Tobacco Res \& Treatment Ctr, Div Gen Med, Boston, MA 02114 USA. Rigotti, Nancy A.; Levy, Douglas E., Harvard Univ, Sch Med, Boston, MA USA. Rigotti, Nancy A.; Levy, Douglas E., Massachusetts Gen Hosp, Mongan Inst Hlth Policy, Boston, MA 02114 USA. Wetherell, LeAnn, Off Medicaid Commonwealth Massachusetts, Boston, MA USA.' article-number: e1000375 author: Land, Thomas and Rigotti, Nancy A. and Levy, Douglas E. and Paskowsky, Mark and Warner, Donna and Kwass, Jo-Ann and Wetherell, LeAnn and Keithly, Lois author-email: Thomas.Land@state.ma.us author_list: - family: Land given: Thomas - family: Rigotti given: Nancy A. - family: Levy given: Douglas E. - family: Paskowsky given: Mark - family: Warner given: Donna - family: Kwass given: Jo-Ann - family: Wetherell given: LeAnn - family: Keithly given: Lois da: '2023-09-28' doi: 10.1371/journal.pmed.1000375 files: [] issn: 1549-1277 journal: PLOS MEDICINE keywords-plus: 'ACUTE MYOCARDIAL-INFARCTION; CORONARY-HEART-DISEASE; SMOKING-CESSATION; UNITED-STATES; QUITTING SMOKING; HEALTH; RISK; MORTALITY; EXPOSURE; CHARGES' language: English month: DEC number: '12' number-of-cited-references: '25' orcid-numbers: Levy, Douglas/0000-0001-9446-7899 papis_id: edd46f9594462421edaa5910efff944a ref: Land2010longitudinalstudy researcherid-numbers: Levy, Douglas/W-1516-2019 times-cited: '37' title: A Longitudinal Study of Medicaid Coverage for Tobacco Dependence Treatments in Massachusetts and Associated Decreases in Hospitalizations for Cardiovascular Disease type: Article unique-id: WOS:000285499600002 usage-count-last-180-days: '0' usage-count-since-2013: '7' volume: '7' web-of-science-categories: Medicine, General \& Internal year: '2010'