abstract: 'Background Social relationships are powerful determinants of health and inequalities in social relationships across socioeconomic status (SES) groups may contribute to social inequalities in health. This study investigates inequalities in social relationships in an international sample of persons with spinal cord injury and explores whether social gradients in relationships are moderated by the countries'' socioeconomic development (SED). Methods Data from 12,330 participants of the International SCI Community Survey (InSCI) performed in 22 countries were used. We regressed social relationships (belongingness, relationship satisfaction, social interactions) on individual SES (education, income, employment, financial hardship, subjective status) and countries'' SED (Human Development Index) using multi-level models (main effects). To test potential moderation of the SED, interaction terms between individual SES and countries'' SED were entered into multi-level models. Results Paid work, absence of financial hardship and higher subjective status were related to higher belongingness (OR, 95\% CI: 1.50, 1.34-1.67; 1.76, 1.53-2.03; 1.16, 1.12-1.19, respectively), higher relationship satisfaction (OR, 95\% CI: 1.28, 1.15-1.42; 1.97, 1.72-2.27; 1.20, 1.17-1.24, respectively) and fewer problems with social interactions (Coeff, 95\% CI: 0.96, 0.82-1.10; 1.93, 1.74-2.12; 0.26, 0.22-0.29, respectively), whereas associations with education and income were less consistent. Main effects for countries'' SED showed that persons from lower SED countries reported somewhat higher relationship satisfaction (OR, 95\% CI: 0.97, 0.94-0.99) and less problems with social interactions (Coeff, 95\% CI: -0.04, -0.09- -0.003). Results from moderation analysis revealed that having paid work was more important for relationships in lower SED countries, while education and subjective status were more important for relationships in higher SED countries (interaction terms p<0.05). Conclusion Social relationships in persons with spinal cord injury are patterned according to individual SES and the countries'' SED and larger socioeconomic structures partly moderate associations between individual SES and social relationships.' affiliation: 'Fekete, C (Corresponding Author), Swiss Parapleg Res, Nottwil, Switzerland. Fekete, C (Corresponding Author), Univ Lucerne, Dept Hlth Sci \& Med, Luzern, Switzerland. Fekete, Christine; Reinhardt, Jan D.; Gross-Hemmi, Mirja; Tough, Hannah, Swiss Parapleg Res, Nottwil, Switzerland. Fekete, Christine; Reinhardt, Jan D.; Tough, Hannah, Univ Lucerne, Dept Hlth Sci \& Med, Luzern, Switzerland. Reinhardt, Jan D., Sichuan Univ, Inst Disaster Management \& Reconstruct Sichuan Un, Chengdu, Peoples R China. Arora, Mohit, Royal North Shore Hosp, John Walsh Ctr Rehabil Res, Kolling Inst Med Res, St Leonards, NSW, Australia. Arora, Mohit, Univ Sydney, Fac Med \& Hlth, Sydney Med Sch Northern, Sydney, NSW, Australia. Engkasan, Julia Patrick, Univ Malaya, Dept Rehabil Med, Kuala Lumpur, Malaysia. Kyriakides, Athanasios, Univ Patras, Spinal Cord Injuries Unit, Patras, Greece. Le Fort, Marc, Univ Hosp, Neurol Phys \& Rehabil Med Dept, Nantes, France.' article-number: e0255448 author: Fekete, Christine and Reinhardt, Jan D. and Arora, Mohit and Engkasan, Julia Patrick and Gross-Hemmi, Mirja and Kyriakides, Athanasios and Le Fort, Marc and Tough, Hannah author-email: christine.fekete@paraplegie.ch author_list: - family: Fekete given: Christine - family: Reinhardt given: Jan D. - family: Arora given: Mohit - family: Engkasan given: Julia Patrick - family: Gross-Hemmi given: Mirja - family: Kyriakides given: Athanasios - family: Le Fort given: Marc - family: Tough given: Hannah da: '2023-09-28' doi: 10.1371/journal.pone.0255448 files: [] issn: 1932-6203 journal: PLOS ONE keywords-plus: 'ENVIRONMENTAL BARRIERS; PSYCHOLOGICAL DISTRESS; HEALTH INEQUALITIES; OLDER-PEOPLE; LONELINESS; SUPPORT; PARTICIPATION; INDIVIDUALS; TRENDS; RISK' language: English number: '8' number-of-cited-references: '67' orcid-numbers: 'Arora, Mohit/0000-0003-1024-3682 Engkasan, Julia Patrick/0000-0003-0599-4908 Kyriakides, Athanasios/0000-0002-4906-6874 Le Fort, Marc/0000-0002-6360-2004' papis_id: 2da59effb1ceeb873989f3bc1057e6d8 ref: Fekete2021socioeconomicstatus researcherid-numbers: 'Arora, Mohit/D-3373-2015 Engkasan, Julia Patrick/M-5547-2018 ' times-cited: '4' title: 'Socioeconomic status and social relationships in persons with spinal cord injury from 22 countries: Does the countries'' socioeconomic development moderate associations?' type: Article unique-id: WOS:000684737400038 usage-count-last-180-days: '2' usage-count-since-2013: '4' volume: '16' web-of-science-categories: Multidisciplinary Sciences year: '2021'