abstract: 'Background Sub-Saharan Africa is one of the highest under-five mortality and low childhood immunization region in the world. Children in Sub-Saharan Africa are 15 times more likely to die than children from high-income countries. In sub-Saharan Africa, more than half of under-five deaths are preventable through immunization. Therefore, this study aimed to identify the determinant factors of full childhood immunization among children aged 12-23 months in sub-Saharan Africa. Methods Data for the study was drawn from the Demographic and Health Survey of nine sub-Saharan African countries. A total of 21,448 children were included. The two-level mixed-effects logistic regression model was used to identify the individual and community-level factors associated with full childhood immunization Result The prevalence of full childhood immunization coverage in sub-Saharan Africa countries was 59.40\% (95\% CI: 58.70, 60.02). The multilevel logistic regression model revealed that secondary and above maternal education (AOR = 1.38; 95\% CI: 1.25, 1.53), health facility delivery (AOR = 1.51; 95\% CI: 1.41, 1.63), fathers secondary education and above (AOR = 1.28, 95\% CI: 1.11, 1.48), four and above ANC visits (AOR = 2.01; 95\% CI: 1.17, 2.30), PNC visit(AOR = 1.55; 95\% CI: 1.46, 1.65), rich wealth index (AOR = 1.26; 95\% CI: 1.18, 1.40), media exposure (AOR = 1.11; 95\% CI: 1.04, 1.18), and distance to health facility is not a big problem (AOR = 1.42; 95\% CI: 1.28, 1.47) were significantly associated with full childhood immunization. Conclusion The full childhood immunization coverage in sub-Saharan Africa was poor with high inequalities. There is a significant variation between SSA countries in full childhood immunization. Therefore, public health programs targeting uneducated mothers and fathers, rural mothers, poor households, and those who have not used maternal health care services to promote full childhood immunization to improve child health. By enhancing institutional delivery, antenatal care visits and maternal tetanus immunization, the government and other stakeholders should work properly to increase child immunization coverage. Furthermore, policies and programs aimed at addressing cluster variations in childhood immunization need to be formulated and their implementation must be strongly pursued.' affiliation: 'Fenta, SM (Corresponding Author), Debre Tabor Univ, Dept Stat Fac Nat \& Computat Sci, Debre Tabor, Ethiopia. Fenta, Setegn Muche; Biresaw, Hailegebrael Birhan; Fentaw, Kenaw Derebe; Gebremichael, Shewayiref Geremew, Debre Tabor Univ, Dept Stat Fac Nat \& Computat Sci, Debre Tabor, Ethiopia.' article-number: '29' author: Fenta, Setegn Muche and Biresaw, Hailegebrael Birhan and Fentaw, Kenaw Derebe and Gebremichael, Shewayiref Geremew author-email: setegn14@gmail.com author_list: - family: Fenta given: Setegn Muche - family: Biresaw given: Hailegebrael Birhan - family: Fentaw given: Kenaw Derebe - family: Gebremichael given: Shewayiref Geremew da: '2023-09-28' doi: 10.1186/s41182-021-00319-x eissn: 1349-4147 files: [] issn: 1348-8945 journal: TROPICAL MEDICINE AND HEALTH keywords: Full immunization; Multi-level analysis; Sub-Saharan Africa keywords-plus: LOGISTIC-REGRESSION; COVERAGE; ETHIOPIA; MORTALITY language: English month: APR 1 number: '1' number-of-cited-references: '44' orcid-numbers: Fenta, Setegn Muche/0000-0003-4006-3455 papis_id: 21b0944c51949a9561f84d9cba8bc28b ref: Fenta2021determinantsfull researcherid-numbers: Fenta, Setegn Muche/ABB-7296-2020 times-cited: '14' title: 'Determinants of full childhood immunization among children aged 12-23 months in sub-Saharan Africa: a multilevel analysis using Demographic and Health Survey Data' type: Article unique-id: WOS:000635910500001 usage-count-last-180-days: '0' usage-count-since-2013: '1' volume: '49' web-of-science-categories: Tropical Medicine year: '2021'